Understanding Atezolizumab (Tecentriq) Immunotherapy in Cancer Treatment

Atezolizumab (Tecentriq) is a cancer immunotherapy drug that works by blocking a protein called programmed death-ligand 1 (PD-L1). PD-L1 is a protein that helps cancer cells evade the immune system. By blocking PD-L1, atezolizumab helps the immune system recognize and attack cancer cells.

Atezolizumab is approved by the U.S. Food and Drug Administration (FDA) to treat a variety of cancers, including:

Non-small cell lung cancer (NSCLC)
Metastatic triple-negative breast cancer
Advanced bladder cancer
Head and neck cancer
Merkel cell carcinoma
Hodgkin lymphoma
MSI-high solid tumors

Atezolizumab is given as an infusion (drip) into a vein. The recommended dose and schedule vary depending on the type of cancer being treated.

Atezolizumab is generally well-tolerated, but it can cause some side effects, such as:

Fatigue
Infusion reactions
Rash
Diarrhea
Nausea and vomiting
Pneumonitis (inflammation of the lungs)
Hepatotoxicity (liver damage)
Hypothyroidism (low thyroid hormone levels)

Serious side effects of atezolizumab can also occur, such as:

Immune-related adverse events (IRAEs), which can affect any part of the body
Death

If you are considering atezolizumab treatment, it is important to weigh the benefits and risks with your doctor.

Here are some additional things to keep in mind about atezolizumab:

It is not a cure for cancer.
It can cause side effects, some of which can be serious.
It is important to monitor your health closely while taking atezolizumab.
If you experience any side effects, tell your doctor right away.

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